Low-dose acitretin therapy may reduce nail psoriasis, research suggests.
(3/17, Preidt) reported that, according to a
published in the March issue of the Archives of Dermatology, "low-dose treatment with" acitretin, "a drug used to treat skin psoriasis, seems to help reduce nail psoriasis." For the study, researchers from Italy's University of Bologna "evaluated the effect of low-dose acitretin therapy (0.2 to 0.3 milligrams per kilogram per day for six months) on the nails of 27 men and nine women...with nail psoriasis." The team followed patients "for at least six months after treatment," and used "the Nail Psoriasis Severity Index...to grade the severity of their condition." After six months, "clinical evaluation" revealed "complete or almost complete clearing of the nail lesions in nine patients (25 percent), moderate improvement in nine (25 percent), mild improvement in 12 (33 percent), and no improvement in six (11 percent)."
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